<p>... you know, maybe i should&#39;ve built a career on molecular biology and not software/hardware, given that my deeply seated desire in a state with zero inhibition seems to be &quot;figure out what the fuck is this protein for&quot;</p>

<p>&#39;Don&#39;t do tracing for Web workloads&#39; - answer by <span class="h-card" translate="no"><a href="https://mstdn.social/@shu" class="u-url mention">@<span>shu</span></a></span> to what the biggest mistakes of Javascript VMs were. <a href="https://www.youtube.com/live/_VF3pISRYRc?t=24797&amp;si=v6QatB4xTj9MAJM0" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://www.</span><span class="ellipsis">youtube.com/live/_VF3pISRYRc?t</span><span class="invisible">=24797&amp;si=v6QatB4xTj9MAJM0</span></a><br />(/cc <span class="h-card" translate="no"><a href="https://mastodon.social/@shriramk" class="u-url mention">@<span>shriramk</span></a></span>)</p>

<p><span class="h-card" translate="no"><a href="https://astolfo.social/@natty" class="u-url mention">@<span>natty</span></a></span> it wasn&#39;t in a single dose this time</p><p>although i did previously take ~3g in 200 mg gel caps by swallowing 15 of them. it&#39;s even more fun if you do it dry! you get to... practice swallowing</p>

<p><span class="h-card" translate="no"><a href="https://awesome.garden/@bytex64" class="u-url mention">@<span>bytex64</span></a></span> oooh, nice!!</p>

@whitequark@mastodon.social how did you even take so many orally

<p>frankly i don&#39;t have patience to deal with Signal Desktop even when sober</p>

<p>i also apparently experienced a *lot* of suicidal ideation at the same time, which i made sure to post only in spoilers and with a clear content warning</p><p>i&#39;m very normal</p>

<p>it&#39;s honestly pretty wild to have a glaring memory gap, go digging through logs and history and such, and discover that despite the extreme impairment what i have done is discuss medical papers with a biologist i know in perfectly clear, grammatically correct English, and in a fairly nuanced way</p>

<p>so yesterday i was feeling badly enough that i took somewhere between 4-5 grams of progesterone. oral p4 is metabolized into allopregnanolone, so this basically had the effect of giving me a deep benzo blackout</p><p>today i&#39;ve retraced all of my steps during the roughly 5-10 hour long blackout interval. in that time i have:<br />- backed up and fixed Signal Desktop<br />- wrangled crypto to buy some estradiol cypionate<br />- discussed in depth the research concerning isoforms of phosphodiesterase 11</p>