<p><span class="h-card" translate="no"><a href="https://hachyderm.io/@fasterthanlime" class="u-url mention">@<span>fasterthanlime</span></a></span> and then we have the two weird ones. modafinil and caffeine</p><p>nobody really knows how modafinil works, but it's probably not by directly influencing dopaminergic/noradrenergic pathways. most likely, the wakefulness promoting effect is downstream of it raising levels of histamine (like the inverse of how 1st gen antihistamines make you sleepy); i don't understand the other effects enough to comment</p><p>(continued)</p>
