<p><span class="h-card" translate="no"><a href="https://mastodon.social/@whitequark" class="u-url mention">@<span>whitequark</span></a></span> <span class="h-card" translate="no"><a href="https://hachyderm.io/@mjk" class="u-url mention">@<span>mjk</span></a></span> In practice, a lot of I2C devices don't go out to lunch (temperature sensors, EEPROMs, etc). I think it's most important to have an out-of-band resettable switch/shifter/mux -- something simple, like a PCA9543 -- in front of any pluggable port, or devices that are known to be problems.</p><p>If you can manage to be able to switch power to the potentially unreliable devices (and your mux/switch tolerates it) that's great too, but often not necessary.</p>